Welcome to the COMET Initiative website

The COMET (Core Outcome Measures in Effectiveness Trials) Initiative brings together people interested in the development and application of agreed standardised sets of outcomes, known as ‘core outcome sets’. These sets represent the minimum that should be measured and reported in all clinical trials of a specific condition, and are also suitable for use in clinical audit or research other than randomised trials. The existence or use of a core outcome set does not imply that outcomes in a particular trial should be restricted to those in the relevant core outcome set. Rather, there is an expectation that the core outcomes will be collected and reported, making it easier for the results of trials to be compared, contrasted and combined as appropriate; while researchers continue to explore other outcomes as well. COMET aims to collate and stimulate relevant resources, both applied and methodological, to facilitate exchange of ideas and information, and to foster methodological research in this area.

Latest News

• Thursday 09 February, 2012 - Driving up the quality and relevance of research through the use of agreed core outcomes
  
  

  P. R. Williamson, et al. (2012), J Health Serv Res Policy January 2012 vol. 17 no. 1 1-2.

• Monday 30 January, 2012 - James Lind Alliance newsletter features COMET article
  
  

  Read about the COMET Initiative, and the importance of patient/service-user opinion in the development of a core outcome set, in the latest addition of the JLA (James Lind Alliance) newsletter .

• Monday 28 November, 2011 - COMET database welcomed by Chair of NIHR HTA Commissioning Board
  
  

  http://www.nihr.ac.uk/Pages/default.aspx

Recently Added Studies

• A systematic review of outcomes assessed in randomized controlled trials of surgical interventions for carpal tunnel syndrome using the International Classification of Functioning, Disability and Health (ICF) as a reference tool
  
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• Current best evidence recommendations on measurement and interpretation of physical function in patients with chronic kidney disease
  
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• PeriNOmS = peripheral neuropathy outcome measures standardization study for inflammatory neuropathies
  
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• Measuring Clinical Severity in Infants with Bronchiolitis
  
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• Core data for nutrition trials in infants: a discussion document--a commentary by the ESPGHAN Committee on Nutrition
  
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