This section of the website includes useful resources and tools. A trio of guidance for COS development now exists, in addition to the COMET Handbook. Click the links below for more information.



The Core Outcome Set-STAndards for Development (COS-STAD) identifies minimum standards for the design of a COS study, and can be used to help users decide whether a COS is relevant and has been developed using a reasonable approach.



The Core Outcome Set-STAndardised Protocol Items (COS-STAP) Statement consists of a checklist of items considered essential in a COS protocol.



The Core Outcome Set-STAndards for Reporting (COS-STAR) provides guidance for the final reporting of COS development studies.

The COMET Handbook: version 1.0


This Handbook, developed by the COMET Initiative, brings together current thinking and methodological research regarding COS development, implementation, evaluation and updating. We recommend a four-step process to develop a COS.

We aim to update the contents of the Handbook periodically as further research is identified. For an up-to-date list of research since the publication of V1.0 of the Handbook, please click here .