Core Outcome Measures in Effectiveness Trials

Patients' opinions on outcomes following critical illness

General Information

Abstract:
BACKGROUND: Our aim was to explore which outcomes are most important to patients following ICU-discharge, and to explore whether intensive care unit (ICU)-nurses and anesthesiologists are aware of patients' priorities. METHODS: First, interviews with adult ICU-survivors were conducted until data saturation was achieved (10 interviews), and six areas with 36 items were identified. Second, interviews with another eight ICU-survivors were conducted, narrowing the list to 20. Finally, patients (inclusion criteria: consecutive adults, medical and surgical, ICU-admission > 5 days, 2-8 months post-ICU discharge) rated the items, as did ICU-nurses and anesthesiologists. RESULTS: A total of 32 patients participated (44% women, medians: age 70.5, time since discharge 179 days, length of stay in ICU 9 days, APACHEII 19.5). The three most important outcomes defined by patients were: lack of physical strength, fatigue, and decreased walking distance. The top three for ICU-nurses (54 participants) were: fatigue, difficulties concentrating, sadness/depression, and for anesthesiologists (17 participants): fatigue, difficulties in activities of daily living, and lack of physical strength. CONCLUSION: Patients chose lack of physical strength, fatigue, and decreased walking distance as the three most important outcomes following critical illness. Physicians had a higher focus on these physical impairments than ICU-nurses.

Authors:
Nedergaard, H. K. Haberlandt, T. Reichmann, P. D. Toft, P. Jensen, H. I.

Publication

Journal:
Acta Anaesthesiol Scand
Volume:
62
Issue:
4
Pages:
531 - 539
Year:
2018
DOI:
Further Study Information

Date:
Not stated
Funding source(s):
This study was conducted as a part of Helene Korvenius Nedergaards PhD-thesis, which is funded by the University of Southern Denmark, Institute for Clinical Research, The Strategic Research Counsil, the Department of anesthesiology and intensive care, Lillebaelt Hospital, Denmark and the Scandinavian Society for Anesthesiology and Intensive Care (SSAI). This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Health Area

Disease Category
Other

Disease Name
Critical illness
Mechanical ventilation

Target Population

Age Range
18 - 100

Sex
Either


Nature / type of Intervention
Unknown

Method(s)

Interview

Stakeholders Involved

Clinical experts
Consumers (patients)

Study Type

Patient perspectives

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