Periprosthetic joint infection (PJI) is a significant complication of joint arthroplasty, however the current literature is limited by variable recording practices and heterogeneity in outcome measures. This inconsistency hinders our ability to evaluate the effectiveness of various treatment strategies, complicating comparisons across studies and limiting the development of evidence-based practices. This project sets out to establish a core outcome set for PJI, addressing the critical need for standardised reporting in future research
ContributorsJohn W Kennedy, Fares S Haddad
Disease Category: Orthopaedics & trauma
Disease Name: Periprosthetic Joint Infection
Age Range: 18 - 100
Sex: Either
Nature of Intervention: Non-surgical, Surgery
- Clinical experts
- Journal editors
- Patient/ support group representatives
- Researchers
- COS for clinical trials or clinical research
- Delphi process
An editorial was published by the authors, appraising the current literature and identifying gaps in current research methodologies. A core group of PJI experts and patients will be established to determine the core outcomes set (COS) for a Delphi process. A Delphi process will be undertaken with a range of key stakeholders, including clinicians and researchers, through online surveys. The level of agreement for accepting outcomes will be set at 75%. Qualitative feedback will also be collected during the process. If additional outcomes, or amendments to the existing outcomes, are recommended by two or more participants these will go forward to the subsequent Delphi rounds. All responses will be anonymous. A summary of the quantitative feedback will be shared anonymously to participants at the end of each round of the Delphi process.