Cancer complicating pregnancy is a rare coexistence. Approximately 1/1000 pregnancies is complicated by any form of malignancy. Incidence of cancer in pregnancy is similar to that of non-pregnant women with the same age. Diagnostic and therapeutic management are more complex as two people are involved. Several collaborative (international) research projects are undertaken to try to optimize diagnostic and therapeutic management in pregnant women who also have cancer.
Trials studying outcomes of mother and fetus in case of malignancy in pregnancy reported different outcomes, resulting in inability to compare studies. It is time to align the outcomes to facilitate the already existing fruitful collaborations t in malignancy and pregnancy studies.
Objective: we aim to develop a core outcome set for pregnancy-related outcomes for pregnancies complicated by malignancy, irrespective of type of malignancy.
dr. S.J. Gordijn, department of Obstetrics, University Medical Center Groningen (UMCG), The Netherlands,
drs. V. Wolters, department of Gynecologic Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
dr. J.W. Ganzevoort, department of Obstetrics, Amsterdam Medical Center (AMC), Amsterdam, The Netherlands.
prof. dr. F. Amant, head CGAO, Antoni van Leeuwenhoek-Netherlands Cancer institue, Amsterdam Medical Center (AMC), The Netherlands.
Disease Category: Cancer, Pregnancy & childbirth
Disease Name: N/A
Age Range: 18 - 48
Nature of Intervention: Any
- Clinical experts
- Consumers (caregivers)
- Consumers (patients)
- Patient/ support group representatives
- COS for clinical trials or clinical research
- COS for practice
- Consensus meeting
- Delphi process
- Literature review
We will start with a review of existing outcomes that will inform the Delphi procedure. If necessary and applicable we will organise a consensus meeting as a satellite meeting of a conference.