RADIATE: Radial Dysplasia; Assessment, Treatment and Aetiology

Aim:
This project aims to develop a core outcome set for radial dysplasia.

Objectives:
1) To perform a systematic review of the literature on radial dysplasia, and produce a comprehensive long list of all outcomes reported in studies of radial dysplasia.
2) To supplement the long list with additional outcomes deemed relevant by patients, their parents, surgeons and hand therapists during the first round of a Delphi process.
3) To use Delphi consensus methods to refine the outcome long-list into a core outcome set agreed by the key stakeholders listed above.
4) To host one or more consensus meetings with the key stakeholders listed, ratify the core outcome set and disseminate it to congenital hand surgeons and researchers globally.

Nature of interventions:
Surgical or non-surgical primary management of radial dysplasia.

Contributors

Supervisors:
Professor Malcolm Logan BSc Phd
Mr Bran Sivakumar, MD FRCS (Plast)
Miss Gill Smith, FRCS (Plast)

Research Fellow:
Mr George Murphy, MA MRCS

Further Study Information

Current Stage: Ongoing
Date: May 2016 - 2020
Funding source(s): TBC


Health Area

Disease Category: Child health, Genetic disorders

Disease Name: Radial dysplasia

Target Population

Age Range: 0 - 100

Sex: Either

Nature of Intervention: Management of care, Surgery

Stakeholders Involved

- Clinical experts
- Families
- Patient/ support group representatives
- Researchers
- Service users

Study Type

- COS for clinical trials or clinical research
- COS for practice

Method(s)

- Consensus meeting
- Delphi process
- Systematic review

The project will involve three stages:
1) All outcome measures reported for radial dysplasia will be gathered by a systematic review of the literature.
2) A three round Delphi process involving key stakeholders (patients, parents, paediatric hand therapists and congenital hand surgeons) will contribute any additional outcomes in the first round, then refine the long list into a core outcome set.
3) The putative core outcome set will be ratified at consensus meetings with the key stakeholders listed.

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