World Health Organization and International League of Associations for Rheumatology core endpoints for symptom modifying antirheumatic drugs in rheumatoid arthritis clinical trials

No abstract available

Aim

One of theobjectives of the conference was to develop consensus on the minimum number of outcome measures to be included in all RA clinical trials. Other objectives included the development of criteria for minimum clinically important improvement in RA patients, and minimum important difference between treatment groups in RA clinical trials; and study of the usefulness of aggregate outcome measures (indices) in the assessment of patients and trials.

Contributors

Boers, M. Tugwell, P. Felson, D. T. van Riel, P. L. Kirwan, J. R. Edmonds, J. P. Smolen, J. S. Khaltaev, N. Muirden, K. D.

Publication

Journal: Journal of Rheumatology - Supplement
Volume: S41
Issue: 21
Pages: 86 - 89
Year: 1994
DOI: None

Further Study Information

Current Stage: Not Applicable
Date: 2002
Funding source(s):

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Method(s)

Methods detailed in:

Fried, B. J., M. Boers, et al. (1993). "A method for achieving consensus on rheumatoid arthritis outcome measures: the OMERACT conference process." Journal of Rheumatology 20(3): 548-51.

Linked Studies

• Outcomes from the Patient Perspective Workshop at OMERACT 6
• OMERACT conference on outcome measures in rheumatoid arthritis clinical trials: introduction
• A method for achieving consensus on rheumatoid arthritis outcome measures: the OMERACT conference process
• Patients' Perspective.
• Developing consensus on preliminary core efficacy endpoints for rheumatoid arthritis clinical trials. OMERACT Committee
• Incorporating the patient perspective into outcome assessment in rheumatoid arthritis - progress at OMERACT 7
• Patient perspective: fatigue as a recommended patient centered outcome measure in rheumatoid arthritis
• A methodological approach for assessing the uptake of core outcome sets using ClinicalTrials.gov: findings from a review of randomised controlled trials of rheumatoid arthritis
• Industry funding was associated with increased use of core outcome sets
• Reporting of patient-reported outcomes in recent trials in rheumatoid arthritis: A systematic literature review
• Outcome measures in rheumatoid arthritis randomised trials over the last 50 years
• Exploring the effect on primary endpoints in trials testing targeted therapy interventions for rheumatoid arthritis: a meta-epidemiological study on the appropriate use of a core outcome set
• Minimal important differences of measurement instruments used in rheumatoid arthritis: a scoping review

Related Links

• OMERACT