Development of a core outcome set for clinical research on interventions for speech impairments in Stroke: COS-Speech

Dysarthria (reduced speech intelligibility) is a common consequence of stroke leading to social isolation and low self-confidence. This speech difficulty after stroke has been neglected with few research studies.

Dysarthria can occur after any type of stroke and varies in severity of impairment.

There are different types of dysarthria (e.g. spastic, hypokinetic), which can also co-occur with and without aphasia (language difficulties). Our Cochrane review of dysarthria intervention found a lack of consensus around outcome measures and the need for a core outcome set for speech recovery was highlighted. A core outcome set would be of use in both clinical practice and research studies to compare the findings from different therapy trials of dysarthria.

Contributors

Lead applicant: Claire Mitchell, University of Manchester
Joint lead applicant: Professor Jamie Kirkham, University of Manchester
Co-applicant: Professor Audrey Bowen, University of Manchester

Co-applicant: Research advisor with lived experience

Further Study Information

Current Stage: Planning
Date: January 2022 - June 2023
Funding source(s): RFPB Research for Patient Benefit


Health Area

Disease Category: Rehabilitation

Disease Name: Stroke

Target Population

Age Range: 18 - 120

Sex: Either

Nature of Intervention: Rehabilitation

Stakeholders Involved

- Clinical experts
- Consumers (patients)
- Researchers

Study Type

- COS for clinical trials or clinical research
- COS for practice
- Recommendations for outcome measures (measurement/how)

Method(s)

- Delphi process
- Systematic review

What to measure?
• To identify a list of potentially important outcome domains for people with dysarthria
• To prioritise and reach consensus regarding these domains from the perspective of patients, clinicians and researchers

How to measure?
• To determine what measures could be used for each domain
• To evaluate and appraise all the measures available using a systematic review process
• Reach consensus on the most appropriate measure for each domain of the core outcome set