Improving service evaluation in clinical genetics: identifying effects of genetic diseases on individuals and families

Outcome measurement in clinical genetics is challenging. Outcome attributes used currently have been developed by service providers or adapted from measures used in other areas of healthcare. Many of the 'patients' in clinical genetics are healthy but at risk of developing or transmitting a condition. Usually no pharmacological or surgical treatment is offered, although information-giving is an objective of most consultations. We argue that services should be evaluated on the basis of how well they alleviate the effects of disease, from a patient perspective. This paper describes a qualitative study using seven focus groups with health professionals, patients and patient representatives. Social and emotional effects of genetics diseases were identified. Some differences emerged between the effects identified by health professionals and those identified by patients. These findings will be used to inform the evaluation of existing outcome measures and develop robust measures of outcome for clinical genetics services.

Aim

These findings will be used to inform the evaluation of existing outcome measures and develop robust measures of outcome for clinical genetics services.

This study forms part of a larger research programme aimed at developing outcome measures for clinical genetics services. The aim in this study was to identify aspects of health and social well-being that are affected by genetic conditions, or risk of genetic conditions, that may be appropriately targeted by clinical genetics services. These could then be used as a first step in identifying valued outcome attributes to be included in the development of new outcome measures and tools.

Contributors

McAllister, Marion; Payne, Katherine; Nicholls, Stuart; MacLeod, Rhona; Donnai, Dian; Davies, Linda M.

Publication

Journal: Journal of Genetic Counseling
Volume: 16
Issue: 1
Pages: 71 - 83
Year: 2007
DOI: 10.1007/s10897-006-9046-3

Further Study Information

Current Stage: Not Applicable
Date:
Funding source(s): Nowgen, the Northwest Genetic Knowledge Park is funded by a grant from the Department of Health and the Department of Trade and Industry. Funding is also acknowledged from CentralManchester and Manchester Children’s University Hospitals NHS Trust and the Universities of Manchester, Liverpool and Lancaster.


Health Area

Disease Category: Genetic disorders

Disease Name:

Target Population

Age Range: 0 - 100

Sex: Either

Nature of Intervention: Not specified

Stakeholders Involved

- Clinical experts
- Consumers (patients)
- Patient/ support group representatives

Study Type

- Patient perspectives
- Prioritising

Method(s)

- Focus group(s)

Health professionals were sent an invitation letter signed by a member of theNowgen team, a participant information sheet and consent form. Patient
representatives were identified through the Genetic Interest Group (GIG) membership list, the Contact a- Family directory, as well as a wider internet search.
Groups identified were asked to nominate a regional representative for the North West. Individuals were then approached and recruited in the same way as
health professionals. Patients who had an appointment with clinical genetics services within the last year, were invited to participate by letter from their
consultant in clinical genetics, supported by a participant information sheet and consent form.