Pharyngitis is a common disease mainly caused by infectious causes such as viruses and bacteria or lifestyle factors such as alcoholism and excessive use of voice. Noncommunicable diseases such as gastroesophageal reflux and recurrent acute pharyngitis also need to be considered. The main clinical manifestations of this disease are repeated hoarseness, irritant cough, sore throat and dysphagia. Sore throats are mostly caused by viral infections, which occur in 5% of children during clinical activities and 2% of outpatient visits, placing a significant financial strain on patients. In the United States, more than 13 million people visit a doctor each year because of the disease. Sore throats cost the UK £400 million a year in lost productivity and doctor visits. Related clinical trials have been on the rise annually. However, the heterogeneity of these trial results pose as an obstacle for synthesizing clinical results in meta-analyses, thus reducing the value of clinical trials. There is also a risk of bias for selective reporting in clinical trials. Therefore, it is necessary and urgent to establish a core outcome set (COS) on for pharyngitis.
ContributorsPrincipal investigator
Pang Wentai, Pang Bo, Zhang Junhua,
Evidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China
Other contributors:
Jin Xinyao, Cao Lujia, Li Yuyun
Evidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China
Disease Category: Lungs & airways
Disease Name: Pharyngitis
Age Range: 6 - 85
Sex: Either
Nature of Intervention: Any
- Clinical experts
- Consumers (patients)
- Epidemiologists
- Ethicists
- Journal editors
- Researchers
- COS for clinical trials or clinical research
- COS for practice
- Consensus conference
- Delphi process
- Interview
- Systematic review
(1) Systematic literature review
(2) Qualitative semi-structured interviews
(3) Two rounds Delphi Survey
(4) Consensus conference