COMET Initiative | Healthcare professionals’ views on the most important outcomes for non-infectious uveitis of the posterior segment: A qualitative study

Healthcare professionals’ views on the most important outcomes for non-infectious uveitis of the posterior segment: A qualitative study

Background
Uveitis comprises a range of conditions that result in intraocular inflammation. Most sight-threatening uveitis falls into the broad category known as Non-infectious Posterior Segment-Involving Uveitis (PSIU). To evaluate treatments, trialists and clinicians must select outcome measures. The aim of this study was to understand healthcare professionals’ perspectives on what outcomes are important to adult patients with PSIU and their carers.

Methods
Twelve semi-structured telephone interviews were undertaken to understand the perspectives of healthcare professionals. Interviews were audio recorded, transcribed and thematically analysed. Findings were compared with the views of patients and carers and outcomes abstracted from a previously published systematic review.

Results
Eleven core domains were identified as important to healthcare professionals: (1) visual function, (2) symptoms, (3) functional ability, (4) impact on relationships, (5) financial impact, (6) psychological morbidity and emotional well-being (7) psychosocial adjustment to uveitis, (8) doctor / patient / interprofessional relationships and access to health care, (9) treatment burden, (10) treatment side effects, (11) disease control. Healthcare professionals recognised a similar range of domains to patients and carers but placed more emphasis on certain outcomes, particularly in the disease control domain. In contrast the range of outcomes identified via the systematic review was limited.

Conclusion
Healthcare professionals recognise all of the published outcome domains as patients/carers in the previous publication but with subtly differing emphasis within some domains and with a priority for certain types of measures. Healthcare professionals discussed the disease control and side effects/complications to a greater degree than patients and carers in the focus groups

Aim

The aim of this study was to understand healthcare professionals’ perspectives on what outcomes are important to adult patients with PSIU and their carers.

Contributors

Mohammad O. Tallouzi, David J. Moore, Nicholas Bucknall, Philip I. Murray, Melanie J. Calvert, Alastair K. Denniston, Jonathan Mathers

Publication

Journal: PLoS ONE
Volume: 18
Issue: 11
Pages: -
Year: 2023
DOI: 10.1371/journal.pone.0294117

Further Study Information

Current Stage: Completed
Date:
Funding source(s): This article represents an independent research project funded by the National Institute for Health Research (NIHR) under the Program Clinical Doctoral Research Fellowship Scheme at the University of Birmingham Award reference: CDRF-2014-05-057

Health Area

Disease Category: Eyes & vision

Disease Name: Uveitis

Target Population

Age Range: 16 - 100

Sex: Either

Nature of Intervention: Any

Stakeholders Involved

- Clinical experts
- Policy makers
- Service commissioners
- Service providers

Study Type

- Recommendations made

Method(s)

- Interview

Twelve semi-structured telephone interviews were undertaken to understand the perspectives of healthcare professionals. Interviews were audio recorded, transcribed and thematically analysed.