Abstract
Introduction
This systematic review is the first step in the process of standardizing outcome reporting through the development of a core outcome set for research on critically ill obstetric patients (COSCO).
Methods
A five-database search was performed to identify randomized and non-randomized studies published before November 2017, on patients admitted to intensive care or high-dependency units during or immediately after pregnancy. Reported outcomes were categorized into domains and definitions were documented.
Results
Of the 12,581 citations reviewed, 136 studies were included. The most reported outcome domains were maternal all-cause mortality (n?=?128, 94.5%), resource use (n?=?116, 85.6%), and clinical/physiological outcomes (n?=?111, 82.8%). Outcomes related to functioning/life impact and adverse effects of treatment were only reported in four (2.9%) studies. There was inconsistency in outcome definitions.
Conclusions
This review identified considerable variation in outcome reporting and definitions and generated an outcome list to consider in COSCO development.
Julien Viau-Lapointe, Julia Kfouri, Mary Thompson, Rizwana Ashraf, Rohan D’Souza, and Stephen Lapinsky
Disease Category: Pregnancy & childbirth
Disease Name: Critical illness , Postpartum Haemorrhage, Severe preeclampsia
Age Range: Unknown
Sex: Female
Nature of Intervention: Management of care
- None
- Systematic review of outcome measures/measurement instruments
- Systematic review of outcomes measured in trials
- Systematic review