Background
The Outcome Measures in Rheumatology (OMERACT) Systemic Lupus Erythematosus (SLE) Working Group held a Special Interest Group (SIG) at the OMERACT 2023 conference in Colorado Springs where SLE collaborators reviewed domain sub-themes generated through qualitative research and literature review.
Objective
The objective of the SIG and the subsequent meetings of the SLE Working Group was to begin the winnowing and binning of candidate domain sub-themes into a preliminary list of candidate domains that will proceed to the consensus Delphi exercise for the SLE COS.
Methods
Four breakout groups at the SLE SIG in Colorado Springs winnowed and binned 132 domain sub-themes into candidate domains, which was continued with a series of virtual meetings by an advisory group of SLE patient research partners (PRPs), members of the OMERACT SLE Working Group Steering Committee, and other collaborators.
Results
The 132 domain sub-themes were reduced to a preliminary list of 20 candidate domains based on their clinical and research relevance for clinical trials and research studies.
Conclusion
A meaningful and substantial winnowing and binning of candidate domains for the SLE COS was achieved resulting in a preliminary list of 20 candidate domains.
Wils Nielsen, Vibeke Strand, Lee S. Simon, Ioannis Parodis, Alfred H.J. Kim, Maya Desai, Yvonne Enman, Daniel Wallace, Yashaar Chaichian, Sandra Navarra, Cynthia Aranow, Meggan MacKay, Kimberly Trotter, Oshrat E. Tayer-Shifman, Ali Duarte-Garcia, Lai Shan Tam, Manuel F. Ugarte-Gil, Guillermo J. PonsEstel, John A. Reynolds, Mandana Nikpour…Zahi Touma
Disease Category: Rheumatology
Disease Name: Systemic lupus erythematosus (SLE)
Age Range: 18
Sex: Either
Nature of Intervention: Any
- Commentary