This scoping review aims to map and describe the outcomes (what has been measured) and outcome measurement instruments (OMIs) in the reconstructive surgical interventions of lower-limb segmental bone defects reported in the published literature on the surgical management of segmental bone defects of the lower limb.
ContributorsZahra Safari1, Ali Yalcinkaya1, Theresa Mann2, Ole Rahbek1,3, Franz Birkholtz2, Søren Kold1
1. Interdisciplinary Orthopaedics, Department of Orthopaedics, Aalborg University Hospital, Aalborg, Denmark.
2. Institute of Orthopedics and Rheumatology, Mediclinic Winelands Orthopedic Hospital, Stellenbosch, South Africa.
3. Department of Orthopaedics, Aarhus University Hospital, Aarhus, Denmark.
Disease Category: Orthopaedics & trauma
Disease Name: Lower-Limb Segmental Bone Defects
Age Range: 18 - 120
Sex: Either
Nature of Intervention: Surgery
- Clinical experts
- Researchers
- Systematic review of outcome measures/measurement instruments
- Systematic review of outcomes measured in trials
- Systematic review
A scoping review of the published literature will be conducted to identify and map outcomes and OMIs across relevant study and patient subgroups. Study selection will be undertaken by two independent reviewers using predefined inclusion and exclusion criteria. For included studies, outcomes, their definitions where reported, the OMIs used, and the timing of outcome assessment will be extracted from both structured outcome fields and relevant free-text sections to avoid omission of important data. Outcomes will be recorded verbatim and primarily mapped to the COMET taxonomy, with further subgrouping or interpretive categorisation informed by the PROLLIT conceptual framework where appropriate. Additional frameworks may be used where necessary to support classification of specific outcomes or instruments. Reference lists of included studies and selected secondary sources will be screened (backward citation search), and forward citation searching
(citation tracking) of included studies will be performed using databases to identify additional eligible primary studies. Findings will be synthesized and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR).