Health and wellbeing outcomes for sex workers: A rapid scoping review

Objectives
Sex workers are vulnerable to adverse health and well-being outcomes and are therefore considered a public health priority. Collecting health and well-being data of sex workers is key to understand the impact of this work. To do this, a core outcome set for this population would be valuable however, this does not currently exist. The aim of this scoping review is to address a key step in developing a core outcome set; to identify the health and well-being outcomes for sex workers that have been reported in the existing literature.

Methods
A rapid scoping review was undertaken (PROSPERO registration number: CRD420261422246). Eligible studies were systematic reviews, scoping reviews, umbrella reviews, and integrative reviews reporting health and/or well-being outcomes of adult (=18 years) sex workers. MEDLINE, PsycINFO, and Epistemonikos were searched from 2016–2026, and citation searching was conducted on the included reviews. The selection process is reported in a PRISMA diagram. Outcomes in the included reviews were extracted using a predefined framework of outcomes.

Results
In total, 42 reviews were included in this rapid scoping review. These reported 264 unique health and well-being outcomes of sex work. Outcomes were identified in physical health (n=55); health behaviour (n=93); mental health (n=40); and well-being (n=76). Physical health outcomes included reproductive, sexual health, and other (e.g. blood borne viruses). Health behaviour outcomes consisted of substance use, healthcare use, sex risk/protection, and other (e.g. harmful vaginal washing). Mental health outcomes comprised mood and anxiety disorders, substance use disorders/symptoms, and other (e.g. suicide ideation). Well-being outcomes included personal well-being and relationships/interactions with others.

Conclusions
These findings represent a key stage in developing a core outcome set for sex worker health and well-being. Using a core outcome set would build a consistent evidence base which is essential to inform health policy for this population.
Other relevant ongoing/developed core outcome sets: HIV/AIDS (ongoing, Engler et. al) mental health (ongoing, Juul et. al), substance-related and addictive disorders (Farrell et al., 2024), reproductive health (ongoing, Mann et. al). However, sex workers are a particularly vulnerable population with increased adverse mental and physical health risks due to specific factors such as unprotected sex, unsafe work environments, difficulty accessing healthcare, and sex work regulation. Therefore, a health and wellbeing core outcome set specifically for this population is needed.

Contributors

Dr Jane Murphy, corresponding/lead author, jamurphy@hrb.ie, Health Research Board Evidence Centre, Dublin, Ireland
Ms Louise Farragher, Health Research Board Evidence Centre, Dublin, Ireland
Dr Áine Teahan, Health Research Board Evidence Centre, Dublin, Ireland

Further Study Information

Current Stage: Ongoing
Date: June 2026 - November 2026
Funding source(s): This review was commissioned by the Department of Health, Ireland


Health Area

Disease Category: Public health

Disease Name: N/A

Target Population

Age Range: 18 - 120

Sex: Either

Nature of Intervention: Any

Stakeholders Involved

- Policy makers
- Researchers

Study Type

- Systematic review of outcomes measured in trials

Method(s)

- Systematic review

A rapid scoping review is being conducted (PROSPERO registration number: CRD420261422246). Eligible studies are systematic reviews, scoping reviews, umbrella reviews, and integrative reviews reporting health and/or well-being outcomes of adult (=18 years) sex workers. MEDLINE, PsycINFO, and Epistemonikos were searched from 2016–2026, and citation searching was conducted on the included reviews. The selection process is reported in a PRISMA diagram. Outcomes in the included reviews were extracted using a predefined framework of outcomes. This review is conducted and reported in line with established guidance on rapid scoping reviews, and the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR).

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