ISARIC - International Severe Acute Respiratory and Emerging Infection Consortium - is a global initiative aiming to ensure that clinical researchers have the open access protocols and data-sharing processes needed to facilitate a rapid response to emerging diseases that may turn into epidemics or pandemics.
Gathering over 70 networks and individuals involved in research related to the outbreaks of diseases such as bird flu (H5N1), swine flu (H1N1) and SARS, the consortium is trying to understand the causes of severe acute respiratory diseases, discover how illnesses develop and progress in patients, and identify the most efficient treatments and the best way to prevent further transmission.
With an overreaching ambition to change the way in which research is carried out during and between epidemics, ISARIC aims to address the social and ethical issues related to this paradigm change.
One aim of ISARIC is to standardize those items of data that are collected by the different research networks conducting clinical and epidemiological research in preparation for and during epidemics and pandemics. Consideration must be given to identifying outcomes measures that have meaning in both low and high resource settings.
A crucial aspect of this process is to identify outcomes of particular importance and relevance. These outcomes will be necessary for meaningful evaluation of the impact of an epidemic or pandemic, and also allow assessment of the benefits and harms of interventions.
***This work completed after R1 of the Delphi***
PI Dr MG (Calum) Semple, University of Liverpool
Dr Ian Sinha, Alder Hey Children’s Hospital, Liverpool
The International Severe Acute Respiratory Infection and Emerging Infection Consortium (ISARIC) see https://isaric.tghn.org/
- Recommendations made
- Delphi process
Multi-round Delphi process
Emailed invitation to contribute
Electronic CRF, themed analysis
ISARIC members, via direct mail
Public via INVOLVE and People in Research website, Facebook and Twitter
Globally, infectious diseases and public health professionals via ProMed e-bulletin.