Background: Perioperative studies of patients following hip fracture have large heterogeneity within their reported outcomes. This study aimed to develop a core outcome set for use in perioperative studies comparing the types of anaesthesia for hip fracture surgery.
Methods: The consensus process consisted of a systematic review of the literature, three rounds of a Delphi survey, two consensus webinars, and face-to-face patient meetings.
Results: The Delphi participants represented nine stakeholder groups. The numbers of participants completing Rounds 1-3 were 242, 186, and 169, respectively. Seventeen outcomes that met the predefined consensus criteria were considered at two consensus meetings. A final set of 10 core outcomes was agreed: mortality, time from injury to surgery, acute coronary syndrome, hypotension, acute kidney injury, delirium, pneumonia, orthogeriatric input, being out of bed at day 1, and pain.
Conclusions: We generated a consensus-based set of core outcomes recommended for use in all perioperative trials evaluating the effects of anaesthesia for hip fracture surgery. An important next step is developing consensus-based consistency on how they should be measured.
C. M. O’Donnell 1,3,*, N. Black1, K. C. McCourt1, M. E. McBrien1, M. Clarke2,
C. C. Patterson2, B. Blackwood3, D. F. McAuley1,3 and M. O. Shields1
1Royal Victoria Hospital, Belfast Health and Social Care Trust, Belfast, UK, 2Centre for Public Health, School
of Medicine, Dentistry and Biomedical Sciences, Institute of Clinical Sciences, Queen’s University Belfast,
Belfast, UK and 3Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and
Biomedical Sciences, Queen’s University Belfast, Belfast, UK
Disease Category: Orthopaedics & trauma
Disease Name: Hip fracture
Age Range: 18 - 100
Sex: Either
Nature of Intervention: Surgery, Procedure
- Clinical experts
- Consumers (patients)
- COS for clinical trials or clinical research
- Delphi process
- Other
- Semi structured discussion
- Systematic review
The consensus process consisted of a systematic review of the literature, three rounds of a Delphi survey, two consensus webinars, and face-to-face patient meetings.