Stroke is a sudden disorder of cerebral blood circulation disease and is divided into acute phase, recovery stage and poststroke syndrome period, which has high incidence rate, lethality rate and disability rate. After the onset of stroke, most of them left some sequelae symptoms, such as dyskinesia, dysphagia and depression. In recent years, the incidence rate of stroke has been increasing year by year, and the age of onset is getting younger. Every year, 5% people in the world suffer from stroke, and more than 5 million patients die of stroke. China is a high incidence area of stroke, which has about 240 new cases every year and the incidence rate is 13.9% per years. About 75% of the survivors have sequelae, 40% of them are severely disabled. Currently, it is the first cause of death in China, which brings huge economic and living burden to the society and patients.
At present, there are no specific treatments for stroke in western medicine clinic, and long-term treatments show great toxic and side effects. However, traditional Chinese medicine in the treatment of stroke have a certain clinical efficacy, and the relevant clinical researches have increased year by year. However, most clinical studies have some problems such as large difference in the selection of outcome indicators, unreported/incomplete report of important outcome indicators, and insufficient reporting of outcome indicators measurement tools/methods. Therefore, it is very necessary and urgent to establish a Core outcome set (COS) on TCM for stroke by scientific research methods.
Ting Zhang. Evidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine;
Mingyan Zhang. Evidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine;
Bohan Niu. Evidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine;
Jinhui Tian. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University;
Junhua Zhang. Evidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine.
Disease Category: Neurology
Disease Name: Stroke
Age Range: 40 - 100
Sex: Either
Nature of Intervention: Complementary and alternative medicine (CAM) therapy, Traditional Chinese Medicine
- Clinical experts
- Consumers (caregivers)
- Consumers (patients)
- Epidemiologists
- Journal editors
- Methodologists
- Patient/ support group representatives
- Researchers
- Statisticians
- COS for practice
- Consensus meeting
- Delphi process
- Interview
- Systematic review
1. Systematic literature review;
2. Qualitative semi-structured interviews;
3. Two rounds Delphi survey;
4. Consensus conference