Core Outcome Set for Melasma

The purpose of this COS is to better detect clinical onset of melasma, and measure change in melasma associated with therapy.


Jennifer Tang, MD
Emily Samuelson, PhD
Matthew Schaeffer, BA
Murad Alam, MD, MSCI (PI) Northwestern University

Further Study Information

Current Stage: Ongoing
Date: July 2015 - May 2023
Funding source(s): Departmental research funds

Health Area

Disease Category: Skin

Disease Name: Melasma

Target Population

Age Range: 18 - 85

Sex: Either

Nature of Intervention: Any

Stakeholders Involved

- Clinical experts
- Consumers (patients)
- Families
- Governmental agencies
- Methodologists
- Pharmaceutical industry representatives

Study Type

- COS for clinical trials or clinical research
- COS for practice


- Consensus conference
- Delphi process
- Focus group(s)
- Interview
- Nominal group technique (NGT)
- Systematic review

Systematic review of outcomes followed by involvement of key stakeholders using interview/focus group/Delphi process. Consolidation of results using NGT and consensus conference.

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