COMET Initiative | Guidelines for controlled trials of drugs in migraine: second edition

Guidelines for controlled trials of drugs in migraine: second edition

Not provided

Aim

In 1991, the Clinical Trials Subcommittee of the International Headache Society (IHS) published its first edition of the guidelines on controlled trials of drugs in migraine. The guidelines were developed because of a need 'to improve the quality of controlled clinical trials in migraine', and because only quality trials can form the basis for international collaboration on drug therapy. Their main purpose was to draw the investigators' attention to the problems inherent in drug trials in migraine. The experience of clinical investigators and the pharmaceutical industry has expanded enormously, providing a basis for revising these guidelines now.

Contributors

Tfelt-Hansen, P. Block, G. Dahlof, C. Diener, H. C. Ferrari, M. D. Goadsby, P. J. Guidetti, V. Jones, B. Lipton, R. B. Massiou, H. Meinert, C. Sandrini, G. Steiner, T. Winter, P. B. International Headache Society Clinical Trials, Subcommittee

Publication

Journal: Cephalalgia
Volume: 20
Issue: 9
Pages: 765 - 86
Year: 2000
DOI: 10.1046/j.1468-2982.2000.00117.x

Further Study Information

Current Stage: Not Applicable
Date:
Funding source(s): Not stated

Health Area

Disease Category: Neurology

Disease Name: Migraine

Target Population

Age Range: 18 - 65

Sex: Either

Nature of Intervention: Drug

Stakeholders Involved

- Clinical experts
- Other (unknown)

Study Type

- Recommendations for outcome measures (measurement/how)
- COS for clinical trials or clinical research